The extract of medicinal aloe leaves, Aloe vera, on the healing of experimental wounds in the rat skin, in a plcebo controlled essay
Abstract
Aloe vera (L.) Burm. f. leaves parenchyma has a kind of mucilage which shows healing, antibacterial, antifungal, anti-inflammatory and antivirotic effects, caused by the presence of anthraquinones such as aloenine, barbaloine and isobarbaloine in their chemical constituency. These phytotherapic properties set them apart among the other species in the Aloe genus. In order to assess this healing capacity of the Aloe vera Glycolic Extract, it was compared to the effect of propylene glycol on wounds experimentally effected on the skin of male Rattus novergicus, of the Wistar lineage. The healing process was followed up for a period of six days, with daily microscopic verification. Finally, a microscopic evaluation of reepitalization was carried out. Results obtained show that the healing process was facilitated by the use of the phytotherapic in the form of glycolic extract, since such extract promoted greater contraction of the experimental wounds. It can also be stated that the tested vehicle, that is, a propilen glycol solution at 50%, did not show relevant differences, when compared to the control group.
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