Analyzing the inflfluence of cortisol levels on the immune system of menopausal women: a systematic review

Authors

  • Thamara Fabricante de Souza Veneroso Escola Superior São Francisco de Assis,
  • Natália Vorpagel Schultz Escola Superior São Francisco de Assis,
  • Karolliny Almeida Araújo Escola Superior São Francisco de Assis,
  • Letícia Karolini Walger Escola Superior São Francisco de Assis,

Abstract

This systematic review article aimed to compile information regarding the influence of the cortisol hormone on the immune system of women during the menopausal phase, highlighting multiple approaches and perspectives. The studies examined cortisol levels in pre- and post-menopausal women, their associations with symptoms such as hot flashes, and the impact of cortisol on quality of life during this phase. Findings revealed a possible connection between elevated cortisol levels and an increased frequency of hot flashes. While some studies indicated a correlation between this hormone and specific symptoms, others did not find significant associations. Additionally, these investigations addressed the relationship between cardiovascular, bone, cognitive, and immune health. Despite the extensive review, there is a notable gap in understanding the influence of cortisol on immunity during menopause, despite its known suppressive properties. Therefore, the complexity of hormonal variations during menopause was underscored, emphasizing the need for further research.

Keywords:

Cortisol; menopause; immunity;

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References

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Vol. 23 No. 1 (2025)

Published:

2025-11-17

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How to Cite

Fabricante de Souza Veneroso, T., Vorpagel Schultz, N., Almeida Araújo, K., & Karolini Walger, L. (2025). Analyzing the inflfluence of cortisol levels on the immune system of menopausal women: a systematic review. Natureza Online, 23(1), 003–014. Retrieved from https://naturezaonline.com.br/revista/article/view/605

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